Can Burna AI grade single-agent trials too?

Yes. A single-agent trial runs on the same engine with one candidate drug instead of several. Every adverse event still gets a CTCAE grade against the trial's version, a MedDRA code, and a WHO-UMC and Kramer assessment for the study drug, and the engine still weighs alternative causes such as the disease itself, concomitant medications and known comorbidities. Citation, clinician review and 21 CFR Part 11 signature work exactly as they do for combination regimens.